Los valores medios de Q albúmina y Q sICAM-1 fueron de 4,1 y 6,2 respectivamente. Los valores medios de sICAM-1 en suero y LCR fueron de 337,4 y 3,97 ng/mL respectivamente. No se encontró síntesis intratecal de inmunoglobulinas. RESULTADOS: Todos los casos evidenciaron hallazgos típicos en los análisis de rutina del LCR y suero: incremento de proteínas totales, aumento de la razón albúmina Q (LCR/suero) acompañado de eosinofilia en LCR. Se tomaron muestras simultáneas de suero y líquido cefalorraquídeo (LCR) en la primera punción lumbar diagnóstica. MÉTODO: Doce niños con meningoencefalitis eosinofílica por Angiostrongylus cantonensis con edades entre 6 y 10 años fueron estudiados. INTRODUCCIÓN: La meningoencefalitis por Angiostrongylus cantonensis es una enfermedad emergente en las Américas. CONCLUSION: It may be suggested that a dynamic of the sICAM-1 brain derived fraction is perhaps associated to the immune response in the evolution of the disease.sICAM-1 may be an agent in negative feedback for eosinophils passage through the blood-CSF barrier into the inflammatory brain response.Īngiostrongylus cantonensis albumin sICAM-1 blood-cerebrospinal fluid barrier eosinophils meningoencephalitis In 50% of the patients an increased brain-derived fraction of sICAM-1 was found. Qalbumin and QsICAM-1 mean values were 4.1 and 6.2 respectively. Mean serum and CSF sICAM-1 values were 337.4 and 3.97 ng/mL. No intrathecal synthesis of immunoglobulins was found. RESULTS: All cases showed typical findings on the routine CSF and serum analysis: increased CSF total protein, increased Q (CSF/serum) albumin accompanied by eosinophilia in CSF.
Cerebrospinal fluid (CSF) and serum samples were taken simultaneously in the first diagnostic puncture at admission. METHOD: Twelve children suffering from eosinophilic meningoencephalitis due to this parasite aged between 6-10 years were studied.
INTRODUCTION: Angiostrongylus cantonensis meningoencephalitis is an emergent disease in the Americas.
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